Despicable Me Wiki
PX41 Rush

The PX-41 Serum appears as an item / power-up in Minion Rush. It first appeared alongside the introduction of Super Silly Fun Land.

In the previous versions (Jelly Lab and before) it could be unlocked after reaching a certain level in the Jelly Lab and upgraded in the Shop. Now, this power-up is not available as stand-alone gadget, but is upgradable via some costume upgrades. In the older versions, the player could touch the part of the screen where a chemical bottle with purple liquid was displayed. When this power-up is picked up,the player's Minion became an Evil Minion frantically destroying anything up to 44 seconds. While running, the minion becomes invincible. After unlocking this item the PX-41 Serum will spawn randomly during runs covered by a fuchsia / purple aura.

Evil Minion

Each Despicable Action caused by destroying obstacles while using the PX-41 rapidly increases the score. This can come in handy when trying to reach a good standing in Minion Leagues and completing missions where the goal is Despicable Actions, making it useful as well as the Freeze Ray and Mega Minion.

This destructive item may seem awesome and make the minion runner invincible, but cannot save it when falling in voids. The PX-41, along with the Freeze Ray, Banana Splitter, Banana Vacuum, Minion Shield and Minion Launcher is one of the few items that does not require the player to tilt the screen in order to use.


  • The icon used to be at the bottom left corner of the screen; due to various complaints about tapping the PX-41's icon accidentally in Minion Rush and activating it, it was later moved to the left part of the screen in later updates, until version 5.7.0.
  • After the 5-Year Celebration update, this power-up can be found during the run just like the rest of the available power-ups.
  • When the minion runner grabs it when already in Evil Minion state, the meter will refill, making the overall duration last longer.
  • In Older versions of Minion Rush after the PX-41 Serum was used, players would have to wait 11 hours to use it again but this wait would get longer if it was upgraded.
  • Prior to the 5-Year Celebration update, this item did not spawn during runs.